Understanding how food leads to fat
The metabolic syndrome (MetS) is a collection of risk factors including high cholesterol, obesity, high blood pressue and insulin resistance, that are associated with an increased risk for type 2 diabetes (DM2) and cardiovascular disease (CVD). Although it is well recognised that lifestyle factors such as poor diet are implicated in the development and progression of MetS, the molecular mechanisms involved in this pathogenic process are still unclear. Our research aims to expand our understanding of how the foods we eat interact with the MetS at the tissue level. Through great understanding of this process we hope to develop better treatment strategies for this disorder and potentially reduce the contribution of the MetS to the increasing global health burden of CVD and DM2.
Dr Scott conducted her undergraduate studies at the University of Otago, New Zealand, graduating with a BSc Honours in Biochemistry in 2003. Her Honours Project was The Effect of Cryoprotective Agents and Freezing on the Redox Status of Murine Fibroblasts. She was awarded a CMRF Summer Studentship in 2003 to determine if Npr-1 knockout and wild-type mice differed in heart weight, blood pressure, infarct size and in plasma levels of cardiac hormones following myocardial infarction.More About Dr Nicola Scott