Obese cancer patients tend to respond more poorly to chemotherapy and have more rapid disease recurrence and shorter survival times. read more
Adipocyte markers as predictors of progression in men with prostate cancerSupport this project
When a man presents with prostate cancer it is difficult to tell whether his cancer is aggressive and needs immediate treatment to prevent it growing and spreading, or whether it is likely to remain dormant and may never need treatment. Recent research has shown fat cells surrounding the prostate can stimulate tumour progression, and we have identified a panel of proteins released by cancer-associated fat cells that promote tumour survival, growth and spread. The overall aim of this study is to test this panel of proteins to see if they can be used to distinguish between dormant and aggressive prostate cancers, and ultimately help men with prostate cancer to undergo fewer unnecessary treatments.
The main focus of Dr Phillips’ research is related to the field of cancer cell biology. Dr Phillips has mainly focused on breast cancer; investigating the mechanisms behind therapy resistance using proteomics and investigating the risk factor obesity and how it contributes to the progression of cancer.More About Dr Elisabeth Phillips